Dana Flavin*
Volume6-Issue3
Dates: Received: 2025-03-03 | Accepted: 2025-03-29 | Published: 2025-03-31
Pages: 309-311
Abstract
While conventional treatments remain central to cancer care, emerging evidence suggests that complementary strategies may modulate tumor progression. This paper outlines an integrated approach that includes detoxification, exercise, nutritional modifications, immune system support, and the use of certain natural compounds. Although preliminary data are promising, further rigorous studies are needed to validate these interventions.
Cancer is a multifaceted disease influenced by genetic, environmental, and lifestyle factors. Recent decades of research have explored various complementary interventions that might help the body combat tumor growth. This manuscript presents an integrated perspective by discussing methods that target multiple pathways involved in cancer progression
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DOI: 10.37871/jbres2085
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© 2025 Flavin D. Distributed under Creative Commons CC-BY 4.0
How to cite this article
Flavin D. Perspectives on an Integrated Approach to Cancer Management. J Biomed Res Environ Sci. 2025 Mar 31; 6(3): 309-311. doi: 10.37871/jbres2085, Article ID: JBRES2085, Available at: https://www.jelsciences. com/articles/jbres2085.pdf
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References
- Singh V, Singh N, Verma M, Kamal R, Tiwari R, Sanjay Chivate M, Rai SN, Kumar A, Singh A, Singh MP, Vamanu E, Mishra V. Hexavalent-Chromium-Induced Oxidative Stress and the Protective Role of Antioxidants against Cellular Toxicity. Antioxidants (Basel). 2022 Nov 30;11(12):2375. doi: 10.3390/antiox11122375. PMID: 36552581; PMCID: PMC9774749.
- Watson B. The detox strategy: vibrant health in 5 easy steps. Simon and Schuster: 2009.
- Schmidinger M. Understanding and managing toxicities of vascular endothelial growth factor (VEGF) inhibitors. EJC Suppl. 2013 Sep;11(2):172-91. doi: 10.1016/j.ejcsup.2013.07.016. PMID: 26217127; PMCID: PMC4041401.
- Carmeliet P. VEGF as a key mediator of angiogenesis in cancer. Oncology. 2005;69 Suppl 3:4-10. doi: 10.1159/000088478. Epub 2005 Nov 21. PMID: 16301830.
- Dhama K, Latheef SK, Dadar M, Samad HA, Munjal A, Khandia R, Karthik K, Tiwari R, Yatoo MI, Bhatt P, Chakraborty S, Singh KP, Iqbal HMN, Chaicumpa W, Joshi SK. Biomarkers in Stress Related Diseases/Disorders: Diagnostic, Prognostic, and Therapeutic Values. Front Mol Biosci. 2019 Oct 18;6:91. doi: 10.3389/fmolb.2019.00091. PMID: 31750312; PMCID: PMC6843074.
- White EG, White J. Counsels on diet and foods. 1946.
- Mosby TT, Cosgrove M, Sarkardei S, Platt KL, Kaina B. Nutrition in adult and childhood cancer: role of carcinogens and anti-carcinogens. Anticancer Res. 2012 Oct;32(10):4171-92. PMID: 23060538.
- Gao X, Sanderson SM, Dai Z, Reid MA, Cooper DE, Lu M, Richie JP Jr, Ciccarella A, Calcagnotto A, Mikhael PG, Mentch SJ, Liu J, Ables G, Kirsch DG, Hsu DS, Nichenametla SN, Locasale JW. Dietary methionine influences therapy in mouse cancer models and alters human metabolism. Nature. 2019 Aug;572(7769):397-401. doi: 10.1038/s41586-019-1437-3. Epub 2019 Jul 31. PMID: 31367041; PMCID: PMC6951023.
- Cavuoto P, Fenech MF. A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension. Cancer Treat Rev. 2012 Oct;38(6):726-36. doi: 10.1016/j.ctrv.2012.01.004. Epub 2012 Feb 17. PMID: 22342103.
- Stiemsma LT, Nakamura RE, Nguyen JG, Michels KB. Does Consumption of Fermented Foods Modify the Human Gut Microbiota? J Nutr. 2020 Jul 1;150(7):1680-1692. doi: 10.1093/jn/nxaa077. PMID: 32232406; PMCID: PMC7330458.
- Jana U. Wonder Probiotics Foods. Chapter 05.
- Fijan S, Fijan P, Wei L, Marco ML. Health benefits of kimchi, sauerkraut, and other fermented foods of the genus brassica. Applied Microbiology. 2024;4(3):1165-1176.
- Sajid MS, Iqbal Z, Muhammad G, Iqbal MU. Immunomodulatory effect of various anti-parasitics: a review. Parasitology. 2006 Mar;132(Pt 3):301-13. doi: 10.1017/S0031182005009108. Epub 2005 Dec 7. PMID: 16332285.
- Mukherjee S, Mukherjee N, Gayen P, Roy P, Babu SP. Metabolic Inhibitors as Antiparasitic Drugs: Pharmacological, Biochemical and Molecular Perspectives. Curr Drug Metab. 2016;17(10):937-970. doi: 10.2174/1389200217666161004143152. PMID: 27719626.
- Ciwun M, Tankiewicz-Kwedlo A, Pawlak D. Low-Dose Naltrexone as an Adjuvant in Combined Anticancer Therapy. Cancers (Basel). 2024 Mar 21;16(6):1240. doi: 10.3390/cancers16061240. PMID: 38539570; PMCID: PMC10968813.
- Dunbar EM, Coats BS, Shroads AL, Langaee T, Lew A, Forder JR, Shuster JJ, Wagner DA, Stacpoole PW. Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors. Invest New Drugs. 2014 Jun;32(3):452-64. doi: 10.1007/s10637-013-0047-4. Epub 2013 Dec 3. PMID: 24297161; PMCID: PMC4455946.
- Belyaev I, Dean A, Eger H, Hubmann G, Jandrisovits R, Kern M, Kundi M, Moshammer H, Lercher P, Müller K, Oberfeld G, Ohnsorge P, Pelzmann P, Scheingraber C, Thill R. EUROPAEM EMF Guideline 2016 for the prevention, diagnosis and treatment of EMF-related health problems and illnesses. Rev Environ Health. 2016 Sep 1;31(3):363-97. doi: 10.1515/reveh-2016-0011. PMID: 27454111.
- Hassan HA, El-Gharib NE, Azhari AF. Role of natural antioxidants in the therapeutic management of hepatocellular carcinoma. Hepatoma Research. 2016;2:216-223.
- Zhou M, Yue Y, Wang Y, Yan S. Polysaccharides from Chinese herbs as natural weapons against colorectal cancer. Biosci Rep. 2023 May 31;43(5):BSR20230041. doi: 10.1042/BSR20230041. PMID: 36951135; PMCID: PMC10196152.